Newer Trends in Antimalarial Chemotherapy
نویسندگان
چکیده
Di & tri substituted imidazoles were prepared by condensing phenylglyoxal with different aryl aldehydes in presence of ammonium acetate and glacial acetic acid. All the di and tri substituted imidazoles were characterized by spectral analysis i.e. HNMR and Mass spectral data. All the synthetic compounds were screened for there anti-inflammatory and anti bacterial activity.
منابع مشابه
Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo.
OBJECTIVES The in vitro and in vivo efficacy and drug-drug interactions of the novel semi-synthetic endoperoxide artemisone with standard antimalarials were investigated in order to provide the basis for the selection of the best partner drug. METHODS Antimalarial activity and drug interactions were evaluated in vitro against Plasmodium falciparum by the incorporation of [(3)H]hypoxanthine. I...
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